| CD59, an LY-6-like protein expressed in human lymphoid cells, regulates the action of the complement membrane attack complex on homologous cells. A Davies, DL Simmons, G Hale, RA Harrison, H Tighe, PJ Lachmann, ... The Journal of experimental medicine 170 (3), 637-654, 1989 | 733 | 1989 |
| Evidence for presence of an internal thiolester bond in third component of human complement. BF Tack, RA Harrison, J Janatova, ML Thomas, JW Prahl Proceedings of the National Academy of Sciences 77 (10), 5764-5768, 1980 | 526 | 1980 |
| The physiological breakdown of the third component of human complement RA Harrison, PJ Lachmann Molecular immunology 17 (1), 9-20, 1980 | 256 | 1980 |
| Structure of a soluble, glycosylated form of the human complement regulatory protein CD59 CM Fletcher, RA Harrison, PJ Lachmann, D Neuhaus Structure 2 (3), 185-199, 1994 | 217 | 1994 |
| Small-molecule factor B inhibitor for the treatment of complement-mediated diseases A Schubart, K Anderson, N Mainolfi, H Sellner, T Ehara, CM Adams, ... Proceedings of the National Academy of Sciences 116 (16), 7926-7931, 2019 | 173 | 2019 |
| Behavior in vivo of normal and dysfunctional C1 inhibitor in normal subjects and patients with hereditary angioneurotic edema. M Quastel, R Harrison, M Cicardi, CA Alper, FS Rosen The Journal of Clinical Investigation 71 (4), 1041-1046, 1983 | 171 | 1983 |
| Human inhibitor of the first component of complement, C1: characterization of cDNA clones and localization of the gene to chromosome 11. AE Davis 3rd, AS Whitehead, RA Harrison, A Dauphinais, GA Bruns, ... Proceedings of the National Academy of Sciences 83 (10), 3161-3165, 1986 | 154 | 1986 |
| Complement and bacterial infections: from molecular mechanisms to therapeutic applications DAC Heesterbeek, ML Angelier, RA Harrison, SHM Rooijakkers Journal of Innate Immunity 10 (5-6), 455-464, 2018 | 149 | 2018 |
| Human C. lovin. 1 inhibitor: improved isolation and preliminary structural characterization RA Harrison Biochemistry 22 (21), 5001-5007, 1983 | 143 | 1983 |
| Physiologic inactivation of fluid phase C3b: isolation and structural analysis of C3c, C3d, g (alpha 2D), and C3g. AE Davis 3rd, RA Harrison, PJ Lachmann Journal of immunology (Baltimore, Md.: 1950) 132 (4), 1960-1966, 1984 | 139 | 1984 |
| Complement technology RA Harrison, PJ Lachmann Handbook of experimental immunology 1, 39.1-39.49, 1986 | 138 | 1986 |
| Characterization of patients with an increased susceptibility to bacterial infections and a genetic deficiency of leukocyte membrane complement receptor type 3 and the related … GD Ross, RA Thompson, MJ Walport, TA Springer, JV Watson, RH Ward, ... | 134 | 1985 |
| A hinge region mutation in C1-inhibitor (Ala436–> Thr) results in nonsubstrate-like behavior and in polymerization of the molecule. KS Aulak, E Eldering, CE Hack, YP Lubbers, RA Harrison, A Mast, ... Journal of Biological Chemistry 268 (24), 18088-18094, 1993 | 126 | 1993 |
| Sequence determination of the thiolester site of the fourth component of human complement. RA Harrison, ML Thomas, BF Tack Proceedings of the National Academy of Sciences 78 (12), 7388-7392, 1981 | 109 | 1981 |
| Structural characterization of factor I mediated cleavage of the third component of complement AE Davis III, RA Harrison Biochemistry 21 (23), 5745-5749, 1982 | 102 | 1982 |
| Isolation and characterization of a membrane protein from rat erythrocytes which inhibits lysis by the membrane attack complex of rat complement TR Hughes, SJ Piddlesden, JD Williams, RA Harrison, BP Morgan Biochemical Journal 284 (1), 169-176, 1992 | 101 | 1992 |
| Analysis of the interactions between properdin, the third component of complement (C3), and its physiological activation products TC Farries, PJ Lachmann, RA Harrison Biochemical Journal 252 (1), 47-54, 1988 | 100 | 1988 |
| Two-domain structure of the native and reactive centre cleaved forms of C1 inhibitor of human complement by neutron scattering SJ Perkins, KF Smith, S Amatayakul, D Ashford, TW Rademacher, ... Journal of molecular biology 214 (3), 751-763, 1990 | 89 | 1990 |
| Molecular cloning of the rat analogue of human CD59: structural comparison with human CD59 and identification of a putative active site NK Rushmere, RA Harrison, CW Van Den Berg, BP Morgan Biochemical Journal 304 (2), 595-601, 1994 | 78 | 1994 |
| Type II hereditary angioneurotic edema that may result from a single nucleotide change in the codon for alanine-436 in the C1 inhibitor gene. NJ Levy, N Ramesh, M Cicardi, RA Harrison, AE Davis 3rd Proceedings of the National Academy of Sciences 87 (1), 265-268, 1990 | 78 | 1990 |
Peter LachmannEmeritus Professor of Immunology, Cambridge UniversityGeverifieerd e-mailadres voor cam.ac.uk
