The 4D nucleome: Evidence for a dynamic nuclear landscape based on co-aligned active and inactive nuclear compartments T Cremer, M Cremer, B Hübner, H Strickfaden, D Smeets, J Popken, ... FEBS letters 589 (20), 2931-2943, 2015 | 246 | 2015 |
Condensed chromatin behaves like a solid on the mesoscale in vitro and in living cells H Strickfaden, TO Tolsma, A Sharma, DA Underhill, JC Hansen, ... Cell 183 (7), 1772-1784. e13, 2020 | 206 | 2020 |
The RNF138 E3 ligase displaces Ku to promote DNA end resection and regulate DNA repair pathway choice IH Ismail, JP Gagné, MM Genois, H Strickfaden, D McDonald, Z Xu, ... Nature cell biology 17 (11), 1446-1457, 2015 | 147 | 2015 |
4D chromatin dynamics in cycling cells: Theodor Boveri's hypotheses revisited H Strickfaden, A Zunhammer, S van Koningsbruggen, D Köhler, T Cremer Nucleus 1 (3), 284-297, 2010 | 121 | 2010 |
A small molecule inhibitor of polycomb repressive complex 1 inhibits ubiquitin signaling at DNA double-strand breaks IH Ismail, D McDonald, H Strickfaden, Z Xu, MJ Hendzel Journal of Biological Chemistry 288 (37), 26944-26954, 2013 | 108 | 2013 |
Poly (ADP-ribosyl) ation-dependent transient chromatin decondensation and histone displacement following laser microirradiation H Strickfaden, D McDonald, MJ Kruhlak, JF Haince, JPH Th'ng, ... Journal of Biological Chemistry 291 (4), 1789-1802, 2016 | 102 | 2016 |
Superresolution imaging of biological nanostructures by spectral precision distance microscopy C Cremer, R Kaufmann, M Gunkel, S Pres, Y Weiland, P Müller, ... Biotechnology journal 6 (9), 1037-1051, 2011 | 80 | 2011 |
The interchromatin compartment participates in the structural and functional organization of the cell nucleus T Cremer, M Cremer, B Hübner, A Silahtaroglu, M Hendzel, C Lanctôt, ... BioEssays 42 (2), 1900132, 2020 | 76 | 2020 |
Double-strand break-induced transcriptional silencing is associated with loss of tri-methylation at H3K4 DM Seiler, J Rouquette, VJ Schmid, H Strickfaden, C Ottmann, GA Drexler, ... Chromosome research 19, 883-899, 2011 | 71 | 2011 |
Recruitment kinetics of DNA repair proteins Mdc1 and Rad52 but not 53BP1 depend on damage complexity V Hable, GA Drexler, T Brüning, C Burgdorf, C Greubel, A Derer, J Seel, ... Public Library of Science 7 (7), e41943, 2012 | 64 | 2012 |
The live cell irradiation and observation setup at SNAKE V Hable, C Greubel, A Bergmaier, P Reichart, A Hauptner, R Krücken, ... Nuclear Instruments and Methods in Physics Research Section B: Beam …, 2009 | 60 | 2009 |
Reprogramming progeria fibroblasts re‐establishes a normal epigenetic landscape Z Chen, WY Chang, A Etheridge, H Strickfaden, Z Jin, G Palidwor, JH Cho, ... Aging cell 16 (4), 870-887, 2017 | 41 | 2017 |
Pin1 promotes histone H1 dephosphorylation and stabilizes its binding to chromatin N Raghuram, H Strickfaden, D McDonald, K Williams, H Fang, C Mizzen, ... Journal of Cell Biology 203 (1), 57-71, 2013 | 39 | 2013 |
Competition effect in DNA damage response C Greubel, V Hable, GA Drexler, A Hauptner, S Dietzel, H Strickfaden, ... Radiation and environmental biophysics 47, 423-429, 2008 | 33 | 2008 |
Remodeling of nuclear architecture by the thiodioxoxpiperazine metabolite chaetocin D Illner, R Zinner, V Handtke, J Rouquette, H Strickfaden, C Lanctôt, ... Experimental cell research 316 (10), 1662-1680, 2010 | 30 | 2010 |
Quantitative analysis of DNA-damage response factors after sequential ion microirradiation C Greubel, V Hable, GA Drexler, A Hauptner, S Dietzel, H Strickfaden, ... Radiation and environmental biophysics 47, 415-422, 2008 | 29 | 2008 |
RYBP is a K63-ubiquitin-chain-binding protein that inhibits homologous recombination repair MAM Ali, H Strickfaden, BL Lee, L Spyracopoulos, MJ Hendzel Cell reports 22 (2), 383-395, 2018 | 28 | 2018 |
DNA-repair protein distribution along the tracks of energetic ions A Hauptner, R Krücken, C Greubel, V Hable, G Dollinger, GA Drexler, ... Radiation protection dosimetry 122 (1-4), 147-149, 2006 | 27 | 2006 |
Spatial distribution of DNA double-strand breaks from ion tracks A Hauptner, W Friedland, S Dietzel, GA Drexler, C Greubel, V Hable, ... Ion beam science: solved and unsolved problems 52, 59-85, 2006 | 26 | 2006 |
Chromosome shattering: a mitotic catastrophe due to chromosome condensation failure B Hübner, H Strickfaden, S Müller, M Cremer, T Cremer European Biophysics Journal 38, 729-747, 2009 | 22 | 2009 |