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Craig Zificsak
Craig Zificsak
Adesis
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Recent advances in the chemistry of ynamines and ynamides
CA Zificsak, JA Mulder, RP Hsung, C Rameshkumar, LL Wei
Tetrahedron 57 (36), 7575-7606, 2001
3272001
Efficient preparations of novel ynamides and allenamides
LL Wei, JA Mulder, H Xiong, CA Zificsak, CJ Douglas, RP Hsung
Tetrahedron 57 (3), 459-466, 2001
1882001
Current methods for the synthesis of 2-substituted azoles
CA Zificsak, DJ Hlasta
Tetrahedron 60 (41), 8991-9016, 2004
1872004
Highly stereoselective synthesis of novel α-haloenamides via a mild and efficient hydrohalogenation of ynamides
JA Mulder, KCM Kurtz, RP Hsung, H Coverdale, MO Frederick, L Shen, ...
Organic Letters 5 (9), 1547-1550, 2003
1442003
The First Stereoselective Ficini− Claisen Rearrangement Using Chiral Ynamides
JA Mulder, RP Hsung, MO Frederick, MR Tracey, CA Zificsak
Organic Letters 4 (8), 1383-1386, 2002
1202002
Intramolecular formal aza-[3+ 3] cycloaddition approach to indoloquinolizidine alkaloids. A stereoselective total synthesis of (±)-tangutorine
S Luo, CA Zificsak, RP Hsung
Organic Letters 5 (24), 4709-4712, 2003
1012003
Lewis Acid Promoted Hetero [2+ 2] Cycloaddition Reactions of Aldehydes with 10-Propynyl-9 (10 H)-acridone. A Highly Stereoselective Synthesis of Acrylic Acid Derivatives and 1 …
RP Hsung, CA Zificsak, LL Wei, CJ Douglas, H Xiong, JA Mulder
Organic Letters 1 (8), 1237-1240, 1999
991999
A formal [3+ 3] cycloaddition reaction. improved reactivity using α, β-unsaturated iminium salts and evidence for reversibility of 6π-electron electrocyclic ring closure of 1 …
HC Shen, J Wang, KP Cole, MJ McLaughlin, CD Morgan, CJ Douglas, ...
The Journal of Organic Chemistry 68 (5), 1729-1735, 2003
852003
Fused bicyclic derivatives of 2, 4-diaminopyrimidine as ALK and c-Met inhibitors
G Ahmed, HJ Breslin, J Burke, MA Curry, JL Diebold, B Dorsey, BJ Dugan, ...
US Patent 8,148,391, 2012
672012
A rare acid-promoted elimination of O-methyl oximes: A practical synthesis of 3-cyano-4-benzopyrones
RP Hsung, CA Zificsak, LL Wei, LR Zehnder, F Park, M Kim, TTT Tran
Journal of organic chemistry 64, 8736-8740, 1999
571999
Combined inhibition of atypical PKC and histone deacetylase 1 is cooperative in basal cell carcinoma treatment
AN Mirza, MA Fry, NM Urman, SX Atwood, J Roffey, GR Ott, B Chen, ...
JCI insight 2 (21), 2017
522017
Total syntheses of enantiomerically enriched R-(+)-and S-(−)-deplancheine
N Sydorenko, CA Zificsak, AI Gerasyuto, RP Hsung
Organic & Biomolecular Chemistry 3 (11), 2140-2144, 2005
382005
Strategies to Mitigate the Bioactivation of 2-Anilino-7-Aryl-Pyrrolo[2,1-f][1,2,4]triazines: Identification of Orally Bioavailable, Efficacious ALK Inhibitors
EF Mesaros, TV Thieu, GJ Wells, CA Zificsak, JC Wagner, HJ Breslin, ...
Journal of Medicinal Chemistry 55 (1), 115-125, 2012
372012
Synthesis and structure–activity relationships of 1, 2, 3, 4-tetrahydropyrido [2, 3-b] pyrazines as potent and selective inhibitors of the anaplastic lymphoma kinase
KL Milkiewicz, LR Weinberg, MS Albom, TS Angeles, M Cheng, AK Ghose, ...
Bioorganic & medicinal chemistry 18 (12), 4351-4362, 2010
352010
Stereoselective trans- and cis-Dihydroxylations of 2H-Pyranyl and Dihydropyridinyl Heterocycles Synthesized from Formal [3 + 3]-Cycloaddition Reactions of α,β …
LR Zehnder, LL Wei, RP Hsung, KP Cole, MJ McLaughlin, HC Shen, ...
Organic Letters 3 (14), 2141-2144, 2001
352001
Pyridopyrazines and derivatives thereof as ALK and c-Met inhibitors
BD Dorsey, KL Milkiewicz, DA Pippin, JP Theroff, T Underiner, ...
US Patent 7,601,716, 2009
312009
Design, synthesis, and biological evaluation of sulfonyl acrylonitriles as novel inhibitors of cancer metastasis and spread
Y Shen, CA Zificsak, JE Shea, X Lao, O Bollt, X Li, JG Lisko, JP Theroff, ...
Journal of Medicinal Chemistry 58 (3), 1140-1158, 2015
302015
A stereoselective intramolecular halo-etherification of chiral enamides in the synthesis of halogenated cyclic ethers
C Ko, RP Hsung, ZF Al-Rashid, JB Feltenberger, T Lu, JH Yang, Y Wei, ...
Organic Letters 9 (22), 4459-4462, 2007
302007
Fused bicyclic derivatives of 2, 4-diaminopyrimidine as c-Met inhibitors
LR Weinberg, MS Albom, TS Angeles, J Husten, JG Lisko, RJ McHugh, ...
Bioorganic & medicinal chemistry letters 21 (1), 164-167, 2011
292011
Synthesis of dihydroxanthone derivatives and evaluation of their inhibitory activity against acetylcholinesterase: Unique structural analogs of tacrine based on the BCD-ring of …
SJ Degen, KL Mueller, HC Shen, JA Mulder, GM Golding, L Wei, ...
Bioorganic & medicinal chemistry letters 9 (7), 973-978, 1999
291999
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