The AC133 epitope, but not the CD133 protein, is lost upon cancer stem cell differentiation K Kemper, MR Sprick, M de Bree, A Scopelliti, L Vermeulen, M Hoek, ... Cancer research 70 (2), 719-729, 2010 | 450 | 2010 |
Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension P Surendran, F Drenos, R Young, H Warren, JP Cook, AK Manning, ... Nature genetics 48 (10), 1151-1161, 2016 | 317 | 2016 |
Chromatin assembly factor 1 is essential and couples chromatin assembly to DNA replication in vivo M Hoek, B Stillman Proceedings of the National Academy of Sciences 100 (21), 12183-12188, 2003 | 299 | 2003 |
Regulated processive transcription of chromatin by T7 RNA polymerase in Trypanosoma brucei E Wirtz, M Hoek, GAM Cross Nucleic Acids Research 26 (20), 4626-4634, 1998 | 143 | 1998 |
The architecture of variant surface glycoprotein gene expression sites in Trypanosoma brucei M Berriman, N Hall, K Sheader, F Bringaud, B Tiwari, T Isobe, S Bowman, ... Molecular and biochemical parasitology 122 (2), 131-140, 2002 | 129 | 2002 |
Role of Swi4 in cell cycle regulation of CLN2 expression FR Cross, M Hoek, JD Mckinney, AH Tinkelenberg Molecular and cellular biology, 1994 | 81 | 1994 |
Exome chip meta-analysis fine maps causal variants and elucidates the genetic architecture of rare coding variants in smoking and alcohol use DM Brazel, Y Jiang, JM Hughey, V Turcot, X Zhan, J Gong, C Batini, ... Biological psychiatry 85 (11), 946-955, 2019 | 72 | 2019 |
Plasma levels of risk-variant APOL1 do not associate with renal disease in a population-based cohort J Kozlitina, H Zhou, PN Brown, RJ Rohm, Y Pan, G Ayanoglu, X Du, ... Journal of the American Society of Nephrology 27 (10), 3204-3219, 2016 | 64 | 2016 |
APOL1 risk allele RNA contributes to renal toxicity by activating protein kinase R K Okamoto, JW Rausch, H Wakashin, Y Fu, JY Chung, PD Dummer, ... Communications biology 1 (1), 188, 2018 | 61 | 2018 |
Trypanosoma brucei expression-site-associated-gene-8 protein interacts with a Pumilio family protein M Hoek, T Zanders, GAM Cross Molecular and biochemical parasitology 120 (2), 269-283, 2002 | 57 | 2002 |
An integrin antagonist (MK‐0429) decreases proteinuria and renal fibrosis in the ZSF 1 rat diabetic nephropathy model X Zhou, J Zhang, R Haimbach, W Zhu, R Mayer‐Ezell, M Garcia‐Calvo, ... Pharmacology research & perspectives 5 (5), e00354, 2017 | 46 | 2017 |
An analysis of CAF-1-interacting proteins reveals dynamic and direct interactions with the KU complex and 14-3-3 proteins M Hoek, MP Myers, B Stillman Journal of Biological Chemistry 286 (12), 10876-10887, 2011 | 46 | 2011 |
Large-insert BAC/YAC libraries for selective re-isolation of genomic regions by homologous recombination in yeast C Zeng, N Kouprina, B Zhu, A Cairo, M Hoek, G Cross, K Osoegawa, ... Genomics 77 (1-2), 27-34, 2001 | 43 | 2001 |
Expression-site-associated gene 8 (ESAG8) of Trypanosoma brucei is apparently essential and accumulates in the nucleolus M Hoek, M Engstler, GAM Cross Journal of cell science 113 (22), 3959-3968, 2000 | 41 | 2000 |
APOL1 renal risk variants promote cholesterol accumulation in tissues and cultured macrophages from APOL1 transgenic mice JH Ryu, M Ge, S Merscher, AZ Rosenberg, M Desante, H Roshanravan, ... PLoS One 14 (4), e0211559, 2019 | 40 | 2019 |
Therapeutics for APOL1 nephropathies: putting out the fire in the podocyte J Heymann, CA Winkler, M Hoek, K Susztak, JB Kopp Nephrology Dialysis Transplantation 32 (suppl_1), i65-i70, 2017 | 40 | 2017 |
APOL1 risk variants affect podocyte lipid homeostasis and energy production in focal segmental glomerulosclerosis M Ge, J Molina, GM Ducasa, SK Mallela, J Varona Santos, A Mitrofanova, ... Human molecular genetics 30 (3-4), 182-197, 2021 | 33 | 2021 |
Molecular profiling reveals a common metabolic signature of tissue fibrosis J Zhang, ES Muise, S Han, PS Kutchukian, P Costet, Y Zhu, Y Kan, ... Cell Reports Medicine 1 (4), 2020 | 33 | 2020 |
APOL1 renal risk variants exacerbate podocyte injury by increasing inflammatory stress H Wakashin, J Heymann, H Roshanravan, P Daneshpajouhnejad, ... BMC nephrology 21, 1-13, 2020 | 22 | 2020 |
PAN-AMPK activation improves renal function in a rat model of progressive diabetic nephropathy X Zhou, ES Muise, R Haimbach, IK Sebhat, Y Zhu, F Liu, SC Souza, ... Journal of Pharmacology and Experimental Therapeutics 371 (1), 45-55, 2019 | 20 | 2019 |