The Pictet–Spengler reaction in nature and in organic chemistry J Stöckigt, AP Antonchick, F Wu, H Waldmann Angewandte Chemie International Edition 50 (37), 8538-8564, 2011 | 689 | 2011 |
Targeting histone methylation for cancer therapy: enzymes, inhibitors, biological activity and perspectives Y Song, F Wu, J Wu Journal of hematology & oncology 9, 1-21, 2016 | 147 | 2016 |
Pharmacological inhibition of LSD1 for the treatment of MLL-rearranged leukemia Z Feng, Y Yao, C Zhou, F Chen, F Wu, L Wei, W Liu, S Dong, M Redell, ... Journal of hematology & oncology 9, 1-13, 2016 | 112 | 2016 |
Discovery, X-ray crystallography and antiviral activity of allosteric inhibitors of flavivirus NS2B-NS3 protease Y Yao, T Huo, YL Lin, S Nie, F Wu, Y Hua, J Wu, AR Kneubehl, MB Vogt, ... Journal of the American Chemical Society 141 (17), 6832-6836, 2019 | 98 | 2019 |
Inhibition of cancer-associated mutant isocitrate dehydrogenases by 2-thiohydantoin compounds F Wu, H Jiang, B Zheng, M Kogiso, Y Yao, C Zhou, XN Li, Y Song Journal of medicinal chemistry 58 (17), 6899-6908, 2015 | 90 | 2015 |
3-(Piperidin-4-ylmethoxy) pyridine containing compounds are potent inhibitors of lysine specific demethylase 1 F Wu, C Zhou, Y Yao, L Wei, Z Feng, L Deng, Y Song Journal of medicinal chemistry 59 (1), 253-263, 2016 | 88 | 2016 |
Die Pictet‐Spengler‐Reaktion in der Natur und der organischen Chemie J Stöckigt, AP Antonchick, F Wu, H Waldmann Angewandte Chemie 123 (37), 8692-8719, 2011 | 68 | 2011 |
Scaffold tailoring by a newly detected Pictet–Spenglerase activity of strictosidine synthase: from the common tryptoline skeleton to the rare piperazino-indole framework F Wu, H Zhu, L Sun, C Rajendran, M Wang, X Ren, S Panjikar, ... Journal of the American Chemical Society 134 (3), 1498-1500, 2012 | 62 | 2012 |
Acetylation of histone H3K27 signals the transcriptional elongation for estrogen receptor alpha Y Gao, L Chen, Y Han, F Wu, WS Yang, Z Zhang, T Huo, Y Zhu, C Yu, ... Communications Biology 3 (1), 165, 2020 | 31 | 2020 |
Synthesis, Structure–Activity Relationships, and Antiviral Activity of Allosteric Inhibitors of Flavivirus NS2B–NS3 Protease S Nie, Y Yao, F Wu, X Wu, J Zhao, Y Hua, J Wu, T Huo, YL Lin, ... Journal of medicinal chemistry 64 (5), 2777-2800, 2021 | 26 | 2021 |
Synthesis, structure-activity relationship and antiviral activity of indole-containing inhibitors of Flavivirus NS2B-NS3 protease S Nie, J Zhao, X Wu, Y Yao, F Wu, YL Lin, X Li, AR Kneubehl, MB Vogt, ... European journal of medicinal chemistry 225, 113767, 2021 | 21 | 2021 |
Discovery, structure–activity relationship, and biological activity of histone-competitive inhibitors of histone acetyltransferases P300/CBP F Wu, Y Hua, S Kaochar, S Nie, YL Lin, Y Yao, J Wu, X Wu, X Fu, R Schiff, ... Journal of medicinal chemistry 63 (9), 4716-4731, 2020 | 20 | 2020 |
Using strictosidine synthase to prepare novel alkaloids H Zhu, P Kercmar, F Wu, C Rajendran, L Sun, M Wang, J Stockigt Current Medicinal Chemistry 22 (15), 1880-1888, 2015 | 20 | 2015 |
Sarpagan-Ajmalan-Type Indoles: Biosynthesis, structural biology, and chemo-enzymatic significance F Wu, P Kerčmar, C Zhang, J Stöckigt The Alkaloids: Chemistry and Biology 76, 1-61, 2016 | 16 | 2016 |
Small-molecule inhibitor of AF9/ENL-DOT1L/AF4/AFF4 interactions suppresses malignant gene expression and tumor growth F Wu, S Nie, Y Yao, T Huo, X Li, X Wu, J Zhao, YL Lin, Y Zhang, Q Mo, ... Theranostics 11 (17), 8172, 2021 | 15 | 2021 |
A proteolysis-targeting chimera molecule selectively degrades ENL and inhibits malignant gene expression and tumor growth X Li, Y Yao, F Wu, Y Song Journal of Hematology & Oncology 15 (1), 41, 2022 | 13 | 2022 |
Glucocorticoids inhibit oncogenic RUNX1-ETO in acute myeloid leukemia with chromosome translocation t (8; 21) L Lu, Y Wen, Y Yao, F Chen, G Wang, F Wu, J Wu, P Narayanan, ... Theranostics 8 (8), 2189, 2018 | 12 | 2018 |
Structure activity relationship and modeling studies of inhibitors of lysine specific demethylase 1 C Zhou, F Wu, L Lu, L Wei, E Pai, Y Yao, Y Song PLoS One 12 (2), e0170301, 2017 | 12 | 2017 |
Determination of 1-deoxynojirimycin in Morus alba L. leaves using reversed-phase high performance liquid chromatography fluorescence detection with pre-column derivatization H Xie, F Wu, Y Yang, J Liu Se pu= Chinese Journal of Chromatography 26 (5), 634-636, 2008 | 11 | 2008 |
Structure-activity relationship and antitumor activity of 1, 4-pyrazine-containing inhibitors of histone acetyltransferases P300/CBP S Nie, F Wu, J Wu, X Li, C Zhou, Y Yao, Y Song European journal of medicinal chemistry 237, 114407, 2022 | 7 | 2022 |