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Joao A Paulo
Joao A Paulo
Instructor in Cell Biology, Harvard Medical School
Geverifieerd e-mailadres voor hms.harvard.edu - Homepage
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The BioPlex network: a systematic exploration of the human interactome
EL Huttlin, L Ting, RJ Bruckner, F Gebreab, MP Gygi, J Szpyt, S Tam, ...
Cell 162 (2), 425-440, 2015
14202015
Architecture of the human interactome defines protein communities and disease networks
EL Huttlin, RJ Bruckner, JA Paulo, JR Cannon, L Ting, K Baltier, G Colby, ...
Nature 545 (7655), 505-509, 2017
13762017
The PINK1-PARKIN mitochondrial ubiquitylation pathway drives a program of OPTN/NDP52 recruitment and TBK1 activation to promote mitophagy
JM Heo, A Ordureau, JA Paulo, J Rinehart, JW Harper
Molecular cell 60 (1), 7-20, 2015
7742015
Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I
K Yamamoto, A Venida, J Yano, DE Biancur, M Kakiuchi, S Gupta, ...
Nature 581 (7806), 100-105, 2020
7482020
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome
EL Huttlin, RJ Bruckner, J Navarrete-Perea, JR Cannon, K Baltier, ...
Cell 184 (11), 3022-3040. e28, 2021
5822021
Detection and quantitation of circulating human irisin by tandem mass spectrometry
MP Jedrychowski, CD Wrann, JA Paulo, KK Gerber, J Szpyt, ...
Cell metabolism 22 (4), 734-740, 2015
5452015
Excessive cell growth causes cytoplasm dilution and contributes to senescence
GE Neurohr, RL Terry, J Lengefeld, M Bonney, GP Brittingham, F Moretto, ...
cell 176 (5), 1083-1097. e18, 2019
4072019
TMTpro reagents: a set of isobaric labeling mass tags enables simultaneous proteome-wide measurements across 16 samples
J Li, JG Van Vranken, L Pontano Vaites, DK Schweppe, EL Huttlin, ...
Nature methods 17 (4), 399-404, 2020
3522020
Defining roles of PARKIN and ubiquitin phosphorylation by PINK1 in mitochondrial quality control using a ubiquitin replacement strategy
A Ordureau, JM Heo, DM Duda, JA Paulo, JL Olszewski, D Yanishevski, ...
Proceedings of the National Academy of Sciences 112 (21), 6637-6642, 2015
3222015
A quantitative tissue-specific landscape of protein redox regulation during aging
H Xiao, MP Jedrychowski, DK Schweppe, EL Huttlin, Q Yu, DE Heppner, ...
Cell 180 (5), 968-983. e24, 2020
2622020
Compensatory metabolic networks in pancreatic cancers upon perturbation of glutamine metabolism
DE Biancur, JA Paulo, B Małachowska, M Quiles Del Rey, CM Sousa, ...
Nature communications 8 (1), 15965, 2017
2582017
Streamlined tandem mass tag (SL-TMT) protocol: an efficient strategy for quantitative (phospho) proteome profiling using tandem mass tag-synchronous precursor selection-MS3
J Navarrete-Perea, Q Yu, SP Gygi, JA Paulo
Journal of proteome research 17 (6), 2226-2236, 2018
2532018
Multidimensional tracking of GPCR signaling via peroxidase-catalyzed proximity labeling
J Paek, M Kalocsay, DP Staus, L Wingler, R Pascolutti, JA Paulo, SP Gygi, ...
Cell 169 (2), 338-349. e11, 2017
2462017
Diabetes relief in mice by glucose-sensing insulin-secreting human α-cells
K Furuyama, S Chera, L van Gurp, D Oropeza, L Ghila, N Damond, ...
Nature 567 (7746), 43-48, 2019
2352019
TEX264 is an endoplasmic reticulum-resident ATG8-interacting protein critical for ER remodeling during nutrient stress
H An, A Ordureau, JA Paulo, CJ Shoemaker, V Denic, JW Harper
Molecular cell 74 (5), 891-908. e10, 2019
2242019
The secreted enzyme PM20D1 regulates lipidated amino acid uncouplers of mitochondria
JZ Long, KJ Svensson, LA Bateman, H Lin, T Kamenecka, IA Lokurkar, ...
Cell 166 (2), 424-435, 2016
2182016
An ancient, unified mechanism for metformin growth inhibition in C. elegans and cancer
L Wu, B Zhou, N Oshiro-Rapley, M Li, JA Paulo, CM Webster, F Mou, ...
Cell 167 (7), 1705-1718. e13, 2016
2132016
Two distinct types of E3 ligases work in unison to regulate substrate ubiquitylation
DC Scott, DY Rhee, DM Duda, IR Kelsall, JL Olszewski, JA Paulo, ...
Cell 166 (5), 1198-1214. e24, 2016
2092016
Probing the global cellular responses to lipotoxicity caused by saturated fatty acids
M Piccolis, LM Bond, M Kampmann, P Pulimeno, C Chitraju, CBK Jayson, ...
Molecular cell 74 (1), 32-44. e8, 2019
2062019
Full-featured, real-time database searching platform enables fast and accurate multiplexed quantitative proteomics
DK Schweppe, JK Eng, Q Yu, D Bailey, R Rad, J Navarrete-Perea, ...
Journal of proteome research 19 (5), 2026-2034, 2020
1992020
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Artikelen 1–20